# Researchers develop promising livestock vaccine against H5N1

> University of Nebraska-Lincoln researchers developed an H5N1 vaccine platform combining intramuscular and intranasal delivery, which protected mice and dairy calves in preclinical tests. The findings are forthcoming in NPJ Vaccines, and no H5N1 vaccine for cattle is currently licensed.

- Date: 2026-04-24 · published 2026-04-24T12:00:00.000Z
- Category: disease · region US · magnitude low
- Page: https://feedsoft.ai/events/15918-researchers-develop-promising-livestock-vaccine-against-h5n1
- Commodities: [Milk (Class III)](https://feedsoft.ai/c/MILK.md)

## Why it matters

A viable cattle vaccine could eventually reduce dairy herd losses and milk output disruption, but it is preclinical and has no near-term effect on feed demand or prices.

## Read by commodity

- MILK: neutral

## Similar past events

| Commodity | Date | Event | 5-day % | 20-day % |
| --- | --- | --- | --- | --- |
| MILK | 2024-10-30 | [Protect Livestock and Public Health from H5N1 Avian Influenza \| APHIS](https://feedsoft.ai/events/16051-protect-livestock-and-public-health-from-h5n1-avian-influenza-aphis.md) | -12.3% | -12.6% |
| MILK | 2024-04-28 | [Influenza A (H5N1) of avian origin in domestic livestock in the USA - GOV.UK](https://feedsoft.ai/events/16098-influenza-a-h5n1-of-avian-origin-in-domestic-livestock-in-the-usa-gov-uk.md) | +18.6% | +19.7% |
| MILK | 2026-03-20 | [Why We Must Vaccinate US Dairy Cattle Against HPAI H5N1 \| The Journal of Infectious Diseases \| Oxford Academic](https://feedsoft.ai/events/15928-why-we-must-vaccinate-us-dairy-cattle-against-hpai-h5n1-the-journal-of.md) | +0.1% | +4.5% |
| MILK | 2025-07-31 | [The changing landscape of Livestock Diseases in 2025 \| CLAL News](https://feedsoft.ai/events/15985-the-changing-landscape-of-livestock-diseases-in-2025-clal-news.md) | +1.6% | +1.8% |
| MILK | 2025-12-19 | [Update: Genetic Sequencing Results for Wisconsin Dairy Herd Detection of Highly Pathogenic Avian Influenza \| APHIS](https://feedsoft.ai/events/15946-update-genetic-sequencing-results-for-wisconsin-dairy-herd-detection-of-highly.md) | +0.4% | -6.6% |

## Sources

- feedstuffs.com: https://www.feedstuffs.com/dairy/researchers-develop-promising-livestock-vaccine-against-h5n1

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Data from Feedsoft AI (https://feedsoft.ai/). For information only; not investment advice.