# Mount Sinai Maps AASS Enzyme, GA1 Target Emerges

> Researchers at the Icahn School of Medicine at Mount Sinai determined the full cryo-EM structure of AASS, the enzyme that starts the lysine breakdown pathway. The study, published in Science Advances on November 13, identified a hinge-like regulatory region that controls the enzyme's activity. The structure gives drug developers a first detailed target for glutaric aciduria type 1, a disorder that can cause brain damage in infants.

- Date: 2026-11-14 · published 2026-11-15T00:13:40.916Z
- Category: report · region US · magnitude low
- Page: https://feedsoft.ai/events/100239-mount-sinai-maps-aass-enzyme-ga1-target-emerges
- Commodities: [Lysine](https://feedsoft.ai/c/LYSINE.md)

## Why it matters

This is a human medical research result with no direct effect on feed grain, oilseed or protein supply, demand or prices.

## Sources

- tmlnews.tech: https://tmlnews.tech/stories/mount-sinai-aass-enzyme-map-ga1/

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Data from Feedsoft AI (https://feedsoft.ai/). For information only; not investment advice.